Detects V617F mutation in the JAK2 gene accurately and quickly with a detection sensitivity of 0.01%.
With a remarkable LoD (Limit of Detection), this kit provides precise information on the JAK2 V617F mutation.
It will help improve research performance on MPNs (myeloproliferative neoplasms).
Both blood and bone marrow samples can be used.
This kit is for Research Use Only (RUO).
Not for use in diagnostic procedures.
FAM | V617F mutant (copies) |
gDNA (copies) |
---|---|---|
Red | 30,000 | 0 |
Orange | 3,000 | 27,000 |
Green | 300 | 29,700 |
Blue | 30 | 29,970 |
Violet | 3 | 29,997 |
Black | 0 | 30,000 |
Exon | Mutation | JAK2 V617F Nucleic Acid Sequence (COSMIC ID) |
---|---|---|
Exon 14 | V617F | 1849G>T (12600) |
Tube | Contents | Quantity |
---|---|---|
JAK2 V617F Master Mixture 1 | 240 μL/tube | |
ADPS™ Smart DNA polymerase | 30 μL/tube | |
JAK2 V617F Positive Control | 50 μL/tube | |
Nuclease-Free Water | 500 μL/tube |
JAK2 V617F | Disease | Frequency | |
---|---|---|---|
MPNs (Myeloproliferative Neoplasms) | PV (Polycythemia Vera) | ≤ 95% | |
ET (Essential Thrombocythemia) | ≤ 60% | ||
PMF (Primary Myelofibrosis) | ≤ 65% |